RITUXIMAB EFFICACY IN TREATING SYSTEMIC JUVENILE ARTHRITIS REFRACTORY TO TRADITIONAL IMMUNOSUPPRESSANT AND TNF BLOCKER THERAPY
The article describes the clinical case of a difficult systemic juvenile arthritis refractory to traditional immunosuppressant and TNF blocker therapy.The disease was Lacrosse - Protective - Arm characterized by such extra-articulate manifestations as fever, lymphadenopathy, hepatolienomegaly, polyorrhymenitis, generalized joint affection and high